Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 19/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22691960 | 0.85 | FGFR2 (0.49) | FGFR2FGFR3FGFR1FGFR4 | |
| SCHEMBL22691719 | 0.85 | FGFR2 (0.49) | FGFR2FGFR3FGFR1FGFR4 | |
| SCHEMBL22691721 | 0.85 | FGFR2 (0.49) | FGFR2FGFR3FGFR1FGFR4 | |
| SCHEMBL22696352 | 0.85 | FGFR2 (0.49) | FGFR2FGFR3FGFR1FGFR4 | |
| SCHEMBL25217016 | 0.84 | FGFR2 (0.39) | FGFR2FGFR3FGFR1FGFR4 | |
| SCHEMBL29535127 | 0.84 | FGFR2 (0.39) | FGFR2FGFR3FGFR1FGFR4 | |
| SCHEMBL29407180 | 0.81 | RIPK1 (0.37) | FGFR2FGFR3FGFR1FGFR4 | |
| SCHEMBL25557463 | 0.81 | FGFR2 (0.46) | FGFR2FGFR3FGFR1FGFR4 | |
| SCHEMBL25557545 | 0.81 | FGFR2 (0.46) | FGFR2FGFR3FGFR1FGFR4 | |
| SCHEMBL25557473 | 0.81 | FGFR2 (0.46) | FGFR2FGFR3FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969442-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | Kinnate Biopharma Inc. (US) | 2022-03-23 | — | — | EP | disclosed |
| WO-2020236524-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. (US) | 2020-11-26 | — | — | WO | disclosed |