Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | IDE | P14735 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HLCS | P50747 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 9/20 | 0.51 |
| ▸ | CA1 | P00915 | 9/20 | 0.51 |
| ▸ | CA2 | P00918 | 9/20 | 0.51 |
| ▸ | CA9 | Q16790 | 9/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726093 | 0.87 | TDP1 (0.73) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13790965 | 0.87 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL22692175 | 0.86 | TDP1 (0.73) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL14572650 | 0.85 | TDP1 (0.64) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13857683 | 0.85 | TDP1 (0.71) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13802847 | 0.84 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL4282638 | 0.81 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL15123570 | 0.80 | TDP1 (0.76) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8126600 | 0.80 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL6036972 | 0.80 | TDP1 (0.76) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269332-A | Compositions and methods relating to tethered ethoxydihydroxybutanone derivatives | 芝加哥大学 | 2022-04-01 | — | — | CN | claimed |
| EP-3972576-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | The University of Chicago (US) | 2022-03-30 | — | — | EP | claimed |
| WO-2020237262-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | THE UNIVERSITY OF CHICAGO (US) | 2020-11-26 | — | — | WO | claimed |
| CN-114269332-A | Compositions and methods relating to tethered ethoxydihydroxybutanone derivatives | 芝加哥大学 | 2022-04-01 | — | — | CN | disclosed |
| EP-3972576-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | The University of Chicago (US) | 2022-03-30 | — | — | EP | disclosed |
| WO-2020237262-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | THE UNIVERSITY OF CHICAGO (US) | 2020-11-26 | — | — | WO | disclosed |