Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | ABL1 | P00519 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | IDE | P14735 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | HLCS | P50747 | 6/20 | 0.59 |
| ▸ | CA12 | O43570 | 7/20 | 0.53 |
| ▸ | CA1 | P00915 | 7/20 | 0.53 |
| ▸ | CA2 | P00918 | 7/20 | 0.53 |
| ▸ | CA9 | Q16790 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14572650 | 0.88 | TDP1 (0.64) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13857683 | 0.88 | TDP1 (0.71) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL22692170 | 0.87 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13802847 | 0.87 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL6036972 | 0.87 | TDP1 (0.76) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL15123570 | 0.87 | TDP1 (0.76) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL28397155 | 0.86 | TDP1 (0.97) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13790965 | 0.86 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL1726151 | 0.86 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL23055065 | 0.85 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473535-B2 | Chemical reagents and methods for detection and quantification of proteins in complex mixtures | THE INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2009-01-06 | — | — | US | claimed |
| US-20220354974-A1 | REAGENTS AND METHODS FOR LABELING MOLECULES WITH ASTATINE ISOTOPES IN HIGHER OXIDATION STATES | UNIVERSITY OF WASHINGTON (US) | 2022-11-10 | — | — | US | disclosed |
| WO-2012034613-A3 | REFRIGERATOR | RED BULL GMBH (AT) | 2012-05-10 | — | — | WO | disclosed |
| EP-1329513-B1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIV WASHINGTON (US) | 2011-12-07 | — | — | EP | disclosed |
| US-7544518-B2 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2009-06-09 | — | — | US | disclosed |
| US-20090111195-A1 | CHEMICAL REAGENTS AND METHODS FOR DETECTION AND QUANTIFICATION OF PROTEINS IN COMPLEX MIXTURES | THE INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2009-04-30 | — | — | US | disclosed |
| US-7473535-B2 | Chemical reagents and methods for detection and quantification of proteins in complex mixtures | THE INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2009-01-06 | — | — | US | disclosed |
| US-20050233399-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2005-10-20 | — | — | US | disclosed |
| US-6852544-B2 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2005-02-08 | — | — | US | disclosed |
| US-20040038319-A1 | Chemical reagents and methods for detection and quantification of proteins in complex mixtures | INSTITUTE FOR SYSTEMS BIOLOGY, THE | 2004-02-26 | — | — | US | disclosed |
| US-6670194-B1 | Mass spectrometry; screening for changes in the expression of enzymatic activity of specific proteins induced by absence, deficiency or excess of a given protein | UNIVERSITY OF WASHINGTON | 2003-12-30 | — | — | US | disclosed |
| EP-1105517-B1 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIV WASHINGTON (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-1329513-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20030087322-A9 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2003-05-08 | — | — | US | disclosed |
| US-20020076739-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2002-06-20 | — | — | US | disclosed |
| EP-1105517-A4 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIV WASHINGTON (US) | 2001-09-19 | — | — | EP | disclosed |
| EP-1105517-A1 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIVERSITY OF WASHINGTON (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000011208-A1 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIVERSITY OF WASHINGTON (US) | 2000-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020076739-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | PRTN3, RPS27A, PA2G4 | TDP1 4040/4885MEN1 2976/4885ABL1 3933/4885 |
| US-20220354974-A1 | REAGENTS AND METHODS FOR LABELING MOLECULES WITH ASTATINE ISOTOPES IN HIGHER OXIDATION STATES | AADAT, CKMT1A; CKMT1B, MB | TDP1 3107/4885MEN1 4288/4885ABL1 924/4885 |
| US-20040038319-A1 | Chemical reagents and methods for detection and quantification of proteins in complex mixtures | STUB1, INHA, IAPP | TDP1 3110/4885MEN1 953/4885ABL1 107/4885 |
| US-20030087322-A9 | Rapid quantitative analysis of proteins or protein function in complex mixtures | PRTN3, RPS27A, PA2G4 | TDP1 4040/4885MEN1 2976/4885ABL1 3933/4885 |
| US-20090111195-A1 | CHEMICAL REAGENTS AND METHODS FOR DETECTION AND QUANTIFICATION OF PROTEINS IN COMPLEX MIXTURES | STUB1, INHA, IAPP | TDP1 3110/4885MEN1 953/4885ABL1 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.