Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.74 |
| ▸ | FYN | P06241 | 7/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | MAP2K5 | Q13163 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 8/20 | 0.37 |
| ▸ | SRC | P12931 | 5/20 | 0.37 |
| ▸ | LYN | P07948 | 4/20 | 0.37 |
| ▸ | FLT3 | P36888 | 4/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.37 |
| ▸ | HCK | P08631 | 3/20 | 0.37 |
| ▸ | FGR | P09769 | 3/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.37 |
| ▸ | BRAF | P15056 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22692841 | 1.00 | MTOR (0.74) | MTORFYNPIK3CDPIK3R2CHEK2 | |
| SCHEMBL22692825 | 0.85 | MTOR (1.00) | MTORFYNPIK3CDPIK3R2CHEK2 | |
| SCHEMBL22664644 | 0.82 | MTOR (0.56) | MTORFYNPIK3CDPIK3R2CHEK2 | |
| SCHEMBL22664622 | 0.78 | MTOR (0.77) | MTORFYNPIK3CDPIK3R2CHEK2 | |
| SCHEMBL22692845 | 0.78 | MTOR (0.77) | MTORFYNPIK3CDPIK3R2CHEK2 | |
| SCHEMBL22664606 | 0.73 | MTOR (1.00) | MTORFYNPIK3CDPIK3R2CHEK2 | |
| SCHEMBL22664645 | 0.72 | MTOR (0.69) | MTORFYNPIK3CDPIK3R2CHEK2 | |
| SCHEMBL22664643 | 0.69 | FYN (0.79) | MTORFYNPIK3CDPIK3R2CHEK2 | |
| SCHEMBL18250076 | 0.68 | ABL1 (0.59) | MTORPIK3CDPIK3CGRETABL1 | |
| SCHEMBL22664630 | 0.67 | FYN (0.76) | MTORFYNPIK3CDPIK3R2CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | SABILA BIOSCIENCES LLC (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | BTK, FYN, YES1 | MTOR 50/4885FYN 2/4885PIK3CD 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.