⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214169 | 0.75 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL2271763 | 0.70 | — | — | |
| SCHEMBL2274719 | 0.68 | — | — | |
| SCHEMBL19547313 | 0.67 | — | — | |
| SCHEMBL6284149 | 0.62 | — | — | |
| SCHEMBL6285994 | 0.59 | — | — | |
| SCHEMBL22435406 | 0.57 | DRD2 (0.38) | — | |
| SCHEMBL18161181 | 0.55 | KDM4E (0.39) | — | |
| SCHEMBL18161170 | 0.54 | POLB (0.33) | — | |
| SCHEMBL15935405 | 0.53 | SMN1; SMN2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-7004979-B2 | Dyeing composition comprising at least one diaminopyrazole oxidation base and at least one pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2006-02-28 | — | — | US | claimed |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | claimed |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-0891181-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2003-05-14 | — | — | EP | claimed |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | L' OREAL S.A. | 2002-01-24 | — | — | US | claimed |
| US-6231623-B1 | OXIDATIVE DYES | L'OREAL S.A. (FR) | 2001-05-15 | — | — | US | claimed |
| EP-2182914-B1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | disclosed |
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | disclosed |
| US-8002847-B2 | Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes | L 'OREAL S.A. (FR) | 2011-08-23 | — | — | US | disclosed |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | disclosed |
| US-20100263138-A1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'OREAL S.A. (FR) | 2010-10-21 | — | — | US | disclosed |
| EP-2182914-A2 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'Oreal (FR) | 2010-05-12 | — | — | EP | disclosed |
| US-7004979-B2 | Dyeing composition comprising at least one diaminopyrazole oxidation base and at least one pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2006-02-28 | — | — | US | disclosed |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | disclosed |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | disclosed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | L' OREAL S.A. | 2002-01-24 | — | — | US | disclosed |
| US-6231623-B1 | OXIDATIVE DYES | L'OREAL S.A. (FR) | 2001-05-15 | — | — | US | disclosed |