Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 8/20 | 0.60 |
| ▸ | RPTOR | Q8N122 | 8/20 | 0.60 |
| ▸ | MLST8 | Q9BVC4 | 8/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133722 | 0.94 | MTOR (0.68) | MTORRPTORMLST8NPSR1SYK | |
| SCHEMBL20129697 | 0.86 | MTOR (0.75) | MTORRPTORMLST8SYKKDM4E | |
| SCHEMBL20133708 | 0.82 | MTOR (0.58) | MTORRPTORMLST8SYKAR | |
| SCHEMBL20149908 | 0.82 | MTOR (0.56) | MTORRPTORMLST8NPSR1SYK | |
| SCHEMBL22188026 | 0.82 | MTOR (0.58) | MTORRPTORMLST8ARPRKCQ | |
| SCHEMBL20133763 | 0.77 | MTOR (0.80) | MTORRPTORMLST8SYKKDM4E | |
| SCHEMBL21360324 | 0.77 | MTOR (0.76) | MTORRPTORMLST8NPSR1KDM4E | |
| SCHEMBL20133689 | 0.76 | MTOR (1.00) | MTORRPTORMLST8KDM4ECA12 | |
| SCHEMBL20133721 | 0.75 | MTOR (0.56) | MTORRPTORMLST8ARKDM4E | |
| SCHEMBL20133670 | 0.74 | MTOR (0.69) | MTORRPTORMLST8LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | MTOR 1/4885RPTOR 3/4885MLST8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.