Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.67 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.67 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22693272 | 0.92 | MTOR (0.67) | MTORRPTORMLST8MAPT | |
| SCHEMBL20149898 | 0.85 | MTOR (0.69) | MTORRPTORMLST8TACR3DRD2 | |
| SCHEMBL20133691 | 0.84 | MTOR (0.69) | MTORRPTORMLST8LMNAALDH1A1 | |
| SCHEMBL20150021 | 0.84 | MTOR (0.70) | MTORRPTORMLST8TACR3DRD4 | |
| SCHEMBL22187975 | 0.84 | MTOR (0.75) | MTORRPTORMLST8TACR3DRD2 | |
| SCHEMBL20133676 | 0.83 | MTOR (0.74) | MTORRPTORMLST8TACR3DRD2 | |
| SCHEMBL20133657 | 0.83 | MTOR (0.84) | MTORRPTORMLST8TACR3DRD2 | |
| SCHEMBL20133659 | 0.83 | MTOR (0.74) | MTORRPTORMLST8TACR3DRD2 | |
| SCHEMBL20133662 | 0.83 | MTOR (0.65) | MTORRPTORMLST8ALDH1A1DRD2 | |
| SCHEMBL20133660 | 0.82 | MTOR (0.72) | MTORRPTORMLST8ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | MTOR 1/4885RPTOR 3/4885MLST8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.