Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL896032 | 0.98 | USP2 (0.55) | USP2CES2HTTMAPTMEN1 | |
| Propylene Glycol SCHEMBL466060 | 0.98 | USP2 (0.55) | USP2CES2HTTMAPTMEN1 | |
| Propylene Glycol SCHEMBL282614 | 0.94 | TSHR (0.50) | USP2CES2HTTMAPTMEN1 | |
| Propylene Glycol SCHEMBL28120659 | 0.91 | TSHR (0.47) | USP2CES2HTTMAPTMEN1 | |
| Propylene Glycol SCHEMBL535932 | 0.90 | USP2 (0.61) | USP2CES2HTTMAPTMEN1 | |
| Propylene Glycol SCHEMBL8961548 | 0.89 | USP2 (0.53) | USP2CES2HTTMAPTMEN1 | |
| Methacrylic Acid SCHEMBL27660622 | 0.88 | TSHR (0.49) | USP2CES2HTTMAPTMEN1 | |
| Propylene Glycol SCHEMBL23159879 | 0.88 | USP2 (0.59) | USP2CES2HTTMAPTMEN1 | |
| Propylene Glycol SCHEMBL8644290 | 0.88 | USP2 (0.64) | USP2CES2HTTMAPTMEN1 | |
| Propylene Glycol SCHEMBL8646850 | 0.88 | USP2 (0.64) | USP2CES2HTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131530-A1 | A CLEANING COMPOSITION FOR METAL SUBSTRATES PRETREATMENT AND ITS PREPARATION METHOD AND APPLICATION THEREOF | BASF COATINGS GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |
| US-10759989-B2 | Temperature-stable paraffin inhibitor compositions | ECOLAB USA INC. (US) | 2020-09-01 | — | — | US | disclosed |
| EP-3400369-A1 | TEMPERATURE-STABLE PARAFFIN INHIBITOR COMPOSITIONS | Ecolab Usa Inc. (US) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017120286-A1 | TEMPERATURE-STABLE PARAFFIN INHIBITOR COMPOSITIONS | ECOLAB USA INC. (US) | 2017-07-13 | — | — | WO | disclosed |
| US-20170190949-A1 | TEMPERATURE-STABLE PARAFFIN INHIBITOR COMPOSITIONS | NORRISEAL-WELLMARK, INC. | 2017-07-06 | — | — | US | disclosed |
| US-8741809-B2 | Liquid pyraclostrobin-containing crop protection formulations | BASF SE (DE) | 2014-06-03 | — | — | US | disclosed |
| US-20110195846-A1 | Liquid Pyraclostrobin-Containing Crop Protection Formulations | BASF SE (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20060177767-A1 | Photosensitive resin composition, thin film panel including a layer made from photosensitive resin composition, and method for manufacturing thin film panel | SAMSUNG ELECTRONICS CO., LTD. | 2006-08-10 | — | — | US | disclosed |