Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL28120659 | 0.96 | TSHR (0.47) | TSHRUSP2ALDH1A1CES2PLA2G2C | |
| Propylene Glycol SCHEMBL2269450 | 0.94 | USP2 (0.52) | TSHRUSP2CES2PLA2G2CMAPT | |
| Propylene Glycol SCHEMBL896032 | 0.92 | USP2 (0.55) | TSHRUSP2CES2PLA2G2CMAPT | |
| Propylene Glycol SCHEMBL466060 | 0.92 | USP2 (0.55) | TSHRUSP2CES2PLA2G2CMAPT | |
| Propylene Glycol SCHEMBL443949 | 0.90 | TSHR (0.48) | TSHRUSP2ALDH1A1CES2PLA2G2C | |
| Propylene Glycol SCHEMBL4954281 | 0.89 | TSHR (0.61) | TSHRUSP2MAPTMEN1THRB | |
| Propylene Glycol SCHEMBL55673 | 0.89 | TSHR (0.61) | TSHRUSP2MAPTMEN1THRB | |
| Methacrylic Acid SCHEMBL27710990 | 0.89 | TSHR (0.44) | TSHRUSP2ALDH1A1CES2PLA2G2C | |
| Glycerin SCHEMBL4324599 | 0.88 | USP2 (0.53) | TSHRUSP2ALDH1A1CES2PLA2G2C | |
| Propylene Glycol SCHEMBL122754 | 0.88 | HSD17B10 (0.52) | TSHRUSP2ALDH1A1CES2PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260147279-A1 | DEVELOPER COMPOSITION FOR METAL-CONTAINING PHOTORESIST, AND METHOD OF FORMING PATTERNS INCLUDING DEVELOPING METHOD USING THE COMPOSITION | SAMSUNG SDI CO., LTD. (KR) | 2026-05-28 | — | — | US | claimed |
| US-20250377591-A1 | PHOTORESIST COMPOSITION AND METHOD FOR FABRICATING SEMICONDUCTOR DEVICE | SAMSUNG ELECTRONICS CO LTD (KR) | 2025-12-11 | — | — | US | claimed |
| CN-119993603-A | Acetic acid-resistant conductive paste, front electrode and solar cell | 成都汉普高新材料有限公司 | 2025-05-13 | — | — | CN | claimed |
| WO-2025073152-A1 | PREPARATION AND DIFFUSION TREATMENT METHOD FOR HIGH-PERFORMANCE DIFFUSION COATING USED FOR SINTERED NEODYMIUM-IRON-BORON MAGNET | 浙江鑫盛永磁科技股份有限公司 | 2025-04-10 | — | — | WO | claimed |
| CN-119751742-A | Photosensitive polyacrylate and preparation method thereof, UV (ultraviolet) glue reducing adhesive tape | 深圳先进电子材料国际创新研究院 | 2025-04-04 | — | — | CN | claimed |
| CN-118995105-B | Conductive silver adhesive for Micro-Led adhesion and preparation method and application method thereof | 先禾新材料(苏州)有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-118109119-B | Long-acting anti-fouling artistic coating and preparation method thereof | 重庆凯茜蔓科技有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119177080-A | Environment-friendly waterproof coating and preparation method thereof | 广东阳光沃土环保科技有限公司 | 2024-12-24 | — | — | CN | claimed |
| CN-118995105-A | Conductive silver adhesive for Micro-Led adhesion and preparation method and application method thereof | 先禾新材料(苏州)有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118983127-A | Heterojunction conductive paste, carrier thereof, preparation and application of carrier resin composition | 长沙连古科技有限公司 | 2024-11-19 | — | — | CN | claimed |
| EP-1720814-A2 | PROCESS FOR RECOVERING ORGANIC COMPOUNDS FROM AQUEOUS STREAMS CONTAINING SAME | The Dow Global Technologies Inc. (US) | 2006-11-15 | — | — | EP | claimed |
| WO-2006110331-A1 | EPOXY SILANE OLIGOMER AND COATING COMPOSITION CONTAINING SAME | GENERAL ELECTRIC COMPANY (US) | 2006-10-19 | — | — | WO | claimed |
| US-20060225613-A1 | Epoxy silane oligomer and coating composition containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-10-12 | — | — | US | claimed |
| US-20060225612-A1 | Epoxy silane oligomer and coating composition containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-10-12 | — | — | US | claimed |
| EP-1638395-A1 | PHYSICAL MODE OF ACTION PESTICIDE | Murphy, Brook Chandler (US) | 2006-03-29 | — | — | EP | claimed |
| WO-2005087692-A2 | PROCESS FOR RECOVERING ORGANIC COMPOUNDS FROM AQUEOUS STREAMS CONTAINING SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-22 | — | — | WO | claimed |
| WO-2005015635-A2 | SPIN ON POLYMERS FOR ORGANIC MEMORY DEVICES | ADVANCED MICRO DEVICES, INC. (US) | 2005-02-17 | — | — | WO | claimed |
| WO-2005000023-A1 | PHYSICAL MODE OF ACTION PESTICIDE | MURPHY BROOK CHANDLER (US) | 2005-01-06 | — | — | WO | claimed |
| US-20040258764-A1 | Polysaccharide comprising xanthan gum, alginate, starch, carrageenan and natural gums; surfactant, cosolvent, and diluent; micelle in colloid suspension; plant growth regulators; decreasing fungus and insect infestation | CAL AGRI PRODUCTS, LLC | 2004-12-23 | — | — | US | claimed |
| US-6656763-B1 | Spin on polymers for organic memory devices | ADVANCED MICRO DEVICES, INC. | 2003-12-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260147279-A1 | DEVELOPER COMPOSITION FOR METAL-CONTAINING PHOTORESIST, AND METHOD OF FORMING PATTERNS INCLUDING DEVELOPING METHOD USING THE COMPOSITION | LBR, AP3D1, AP2S1 | TSHR 2430/4885USP2 3337/4885ALDH1A1 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.