SCHEMBL22694605

SCHEMBL22694605

CCCCCCN(/N=C/c1cc(I)c(C(C)(C)C)cc1I)c1nc2ccccc2s1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 4/20 0.36
▸ RAB9A P51151 4/20 0.36
▸ ALDH1A1 P00352 3/20 0.36
▸ GAA P10253 2/20 0.34
▸ ATP4A P20648 11/20 0.33
▸ ATP4B P51164 11/20 0.33
▸ RAD52 P43351 1/20 0.33
▸ MAPT P10636 2/20 0.32
▸ TP53 P04637 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ STAT1 P42224 1/20 0.31
▸ NFKB2 Q00653 1/20 0.31
▸ RELA Q04206 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ DHODH Q02127 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21868806 0.86 NPC1 (0.38) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL22700829 0.85 ALDH1A1 (0.37) NPC1RAB9AALDH1A1GAARAD52
SCHEMBL22699682 0.80 TNF (0.41) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL18873388 0.79 ALDH1A1 (0.39) NPC1RAB9AALDH1A1GAARAD52
SCHEMBL18873368 0.79 ALDH1A1 (0.39) NPC1RAB9AALDH1A1GAARAD52
SCHEMBL21868807 0.79 NPC1 (0.43) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL18079683 0.78 SNCA (0.46) NPC1RAB9AALDH1A1GAARAD52
SCHEMBL27308111 0.78 NPC1 (0.38) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL15722737 0.78 SNCA (0.46) NPC1RAB9AALDH1A1GAARAD52
SCHEMBL19621642 0.78 NPC1 (0.46) NPC1RAB9AALDH1A1GAAATP4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518938-B2 Optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 — — US disclosed
US-11370970-B2 Optically anisotropic film, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2022-06-28 — — US disclosed
US-20200399538-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-12-24 — — US disclosed
US-20200369960-A1 OPTICALLY ANISOTROPIC FILM, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-11-26 — — US disclosed
US-20200369961-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-11-26 — — US disclosed
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