Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | NPY4R | P50391 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | NPY1R | P25929 | 3/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22267878 | 1.00 | FAP (0.37) | FAPPTGS1PTGS2NPY4RNPY5R | |
| SCHEMBL18909025 | 1.00 | FAP (0.37) | FAPPTGS1PTGS2NPY4RNPY5R | |
| SCHEMBL20935173 | 0.94 | ELANE (0.34) | FAPNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL20340684 | 0.92 | FAP (0.37) | FAPPTGS1PTGS2NPY4RNPY5R | |
| SCHEMBL19170705 | 0.91 | PTGS1 (0.34) | FAPPTGS1PTGS2ELANEFURIN | |
| SCHEMBL19681474 | 0.91 | NPY5R (0.39) | FAPPTGS1PTGS2NPY4RNPY5R | |
| SCHEMBL29308956 | 0.91 | NPY5R (0.40) | FAPPTGS1PTGS2NPY4RNPY5R | |
| SCHEMBL23436443 | 0.91 | FAP (0.34) | FAPPTGS1PTGS2NPY4RNPY5R | |
| SCHEMBL22668644 | 0.91 | FAP (0.34) | FAPPTGS1PTGS2NPY4RNPY5R | |
| SCHEMBL23420959 | 0.90 | FAP (0.37) | FAPPTGS1PTGS2NPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020236795-A2 | TRISPECIFIC BINDING MOLECULES AGAINST BCMA AND USES THEREOF | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |