⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22695463 | 0.89 | ALPL (0.32) | — | |
| SCHEMBL22803217 | 0.82 | — | — | |
| SCHEMBL22803215 | 0.72 | ALPL (0.32) | — | |
| SCHEMBL22695469 | 0.71 | NTRK1 (0.31) | — | |
| SCHEMBL22695468 | 0.71 | MAP4K1 (0.31) | — | |
| SCHEMBL22695445 | 0.68 | NR3C2 (0.39) | — | |
| SCHEMBL21334405 | 0.67 | MAP4K1 (0.46) | — | |
| SCHEMBL22695460 | 0.65 | MAP4K1 (0.39) | — | |
| SCHEMBL23790732 | 0.64 | — | — | |
| SCHEMBL24283955 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020237025-A1 | SUBSTITUTED EXO-METHYLENE-OXINDOLES WHICH ARE HPK1/MAP4K1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2020-11-26 | — | — | WO | disclosed |