⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132184 | 0.75 | — | — | |
| SCHEMBL22655794 | 0.74 | — | — | |
| SCHEMBL17630812 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL23888107 | 0.72 | — | — | |
| SCHEMBL21222751 | 0.70 | — | — | |
| SCHEMBL16704390 | 0.69 | — | — | |
| SCHEMBL11971096 | 0.63 | — | — | |
| SCHEMBL25254403 | 0.63 | EPHX1 (0.52) | — | |
| SCHEMBL24616401 | 0.62 | — | — | |
| SCHEMBL521656 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024167922-A2 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-08-15 | — | — | WO | disclosed |
| EP-3747869-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-20200369621-A1 | SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| CN-109776512-A | N-substituted imidazole formate derivative and application thereof | 成都安诺晨创医药科技有限公司 | 2019-05-21 | — | — | CN | disclosed |