SCHEMBL24616401

SCHEMBL24616401

N#CC1(CO)CCOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1565996 0.86 DPP4 (0.37)
SCHEMBL17630812 0.81
SCHEMBL24616328 0.74
SCHEMBL101460 0.73
SCHEMBL4126698 0.69
SCHEMBL101752 0.69
SCHEMBL12077935 0.68
SCHEMBL20742567 0.68
SCHEMBL1192219 0.68 AOC2 (0.34)
SCHEMBL24711335 0.68 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545684-B2 CDK2 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2026-02-10 US disclosed
US-20250221996-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE, LTD. (KY) 2025-07-10 US disclosed
EP-4536356-A1 PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS Xenon Pharmaceuticals Inc. (CA) 2025-04-16 EP disclosed
US-20240383902-A1 CDK2 INHIBITORS BLUEPRINT MEDICINES CORPORATION 2024-11-21 US disclosed
US-20240140957-A1 BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF BEONE MEDICINES I GMBH (CH) 2024-05-02 US disclosed
US-11970498-B2 CDK2 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2024-04-30 US disclosed
US-20240101531-A1 PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS XENON PHARMACEUTICALS INC. (CA) 2024-03-28 US disclosed
US-11932648-B2 CDK2 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2024-03-19 US disclosed
WO-2023239729-A1 PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS XENON PHARMACEUTICALS INC. (CA) 2023-12-14 WO disclosed
US-20230322791-A1 CDK2 INHIBITORS BLUEPRINT MEDICINES CORPORATION 2023-10-12 US disclosed
US-20230159535-A1 CDK2 INHIBITORS BLUEPRINT MEDICINES CORPORATION 2023-05-25 US disclosed
WO-2022148422-A1 BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF BEIGENE, LTD. (KY) 2022-07-14 WO disclosed