SCHEMBL22697254

SCHEMBL22697254

CCOCC(CBr)OCC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL208312 0.84 THRB (0.42) THRBLMNA
SCHEMBL11955576 0.81 THRB (0.40) THRBLMNA
SCHEMBL10023016 0.81 THRB (0.40) THRBLMNA
SCHEMBL21618241 0.81
SCHEMBL9602518 0.80 THRB (0.35) THRBLMNA
SCHEMBL18973894 0.80
SCHEMBL18973933 0.80
SCHEMBL14032073 0.80
SCHEMBL242883 0.79 THRB (0.38) THRBLMNA
Water SCHEMBL4365142 0.77 THRB (0.36) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020233716-A1 IMIDAZOPYRIDAZINE MNK1/MNK2 KINASE INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF 上海道熵生物科技有限公司 (CN) 2020-11-26 WO disclosed