SCHEMBL22698402

SCHEMBL22698402

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nccc5sc6ccc(-c7ccc8c9ccccc9c9ccccc9c8c7)cc6c45)cc3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROCK1 Q13464 1/20 0.39
KMT2A Q03164 3/20 0.37
ATM Q13315 2/20 0.37
MEN1 O00255 2/20 0.37
PDE3B Q13370 2/20 0.37
PDE3A Q14432 2/20 0.37
LIMK1 P53667 2/20 0.36
KDM4E B2RXH2 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
GPR55 Q9Y2T6 1/20 0.34
MAPT P10636 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22698298 0.84 MEN1 (0.38) ROCK1KMT2AATMMEN1PDE3B
SCHEMBL19802290 0.81 MEN1 (0.41) ROCK1KMT2AATMMEN1LIMK1
SCHEMBL25463055 0.80 MEN1 (0.35) ROCK1KMT2AATMMEN1PDE3B
SCHEMBL19802644 0.80 F9 (0.36) ROCK1KMT2AATMMEN1LIMK1
SCHEMBL20391967 0.80 F9 (0.39) ROCK1KMT2AATMMEN1LIMK1
SCHEMBL19802065 0.79 F9 (0.39) ROCK1KMT2AATMMEN1LIMK1
SCHEMBL19802881 0.79 F9 (0.36) ROCK1KMT2AATMMEN1LIMK1
SCHEMBL25646127 0.79 PIM3 (0.38) ROCK1KMT2AATMMEN1LIMK1
SCHEMBL24169841 0.79 GPR3 (0.42) ROCK1KMT2AATMMEN1LIMK1
SCHEMBL24169330 0.79 GPR3 (0.42) ROCK1KMT2AATMMEN1LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019212287-A9 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 (KR) 2020-11-26 WO disclosed