SCHEMBL22698482

SCHEMBL22698482

Clc1cncc2oc3ccc(-c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4-5)cc3c12

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
AHR P35869 1/20 0.33
PDK2 Q15119 9/20 0.32
WEE1 P30291 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
OPRK1 P41145 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22698394 0.84 PDK2 (0.31) PDK2WEE1KDM4EMEN1LMNA
SCHEMBL22698393 0.81 LPL (0.30)
SCHEMBL22698400 0.80 AHR (0.43) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL18086163 0.79 MAPT (0.40) AHRPDK2KDM4EMEN1LMNA
SCHEMBL22698448 0.78 PDK2 (0.33) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL24795251 0.77 PDK2 (0.33) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25052975 0.76 KMT2A (0.35) AHRPDK2KDM4EMEN1LMNA
SCHEMBL25023168 0.76 PDK2 (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL24795421 0.76 PDK2 (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL20127303 0.76 ABCG2 (0.37) AHRWEE1KDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019212287-A9 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 (KR) 2020-11-26 WO disclosed