Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239561 | 1.00 | ATM (0.52) | ATMALDH1A1HPGDMAPTHTT | |
| SCHEMBL14536984 | 1.00 | ATM (0.52) | ATMALDH1A1HPGDMAPTHTT | |
| SCHEMBL84627 | 1.00 | ATM (0.52) | ATMALDH1A1HPGDMAPTHTT | |
| SCHEMBL13239540 | 1.00 | ATM (0.52) | ATMALDH1A1HPGDMAPTHTT | |
| SCHEMBL14527535 | 1.00 | ATM (0.52) | ATMALDH1A1HPGDMAPTHTT | |
| SCHEMBL19303302 | 0.86 | ATM (0.44) | ATMALDH1A1HPGDMAPTHTT | |
| SCHEMBL14378375 | 0.77 | ALDH1A1 (0.46) | ATMALDH1A1HPGDMAPTHTT | |
| SCHEMBL14378694 | 0.77 | ALDH1A1 (0.46) | ATMALDH1A1HPGDMAPTHTT | |
| SCHEMBL10126356 | 0.77 | ALDH1A1 (0.46) | ATMALDH1A1HPGDMAPTHTT | |
| SCHEMBL18912900 | 0.76 | ATM (0.52) | ATMALDH1A1HPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210330693-A1 | HEPARANASE INHIBITORS AND THEIR USE AS ANTI-CANCER COMPOUNDS | WAYNE STATE UNIVERSITY (US) | 2021-10-28 | — | — | US | disclosed |
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-10-14 | — | — | US | disclosed |
| WO-2020236253-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-26 | — | — | WO | disclosed |
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | BRCA1, BTD, BCHE | ATM 4226/4885ALDH1A1 731/4885HPGD 162/4885 |
| US-20210330693-A1 | HEPARANASE INHIBITORS AND THEIR USE AS ANTI-CANCER COMPOUNDS | HPSE, ENGASE, FUCA1 | ATM 4352/4885ALDH1A1 2582/4885HPGD 1151/4885 |
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | BRCA1, BTD, BCHE | ATM 4226/4885ALDH1A1 731/4885HPGD 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.