Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.65 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16633487 | 0.79 | MGLL (0.77) | MGLLCYP2A6BCL2L1HDAC3HDAC4 | |
| SCHEMBL8212 | 0.79 | MGLL (1.00) | MGLLCYP2A6BCL2L1HDAC3HDAC4 | |
| Boric Acid SCHEMBL28420308 | 0.77 | MGLL (0.96) | MGLLCYP2A6BCL2L1HDAC3HDAC4 | |
| SCHEMBL793130 | 0.76 | MGLL (0.71) | MGLLCYP2A6BCL2L1HDAC3HDAC4 | |
| SCHEMBL12513342 | 0.75 | MGLL (0.65) | MGLLCYP2A6BCL2L1ERN1HDAC3 | |
| SCHEMBL19833867 | 0.74 | MGLL (0.69) | MGLLCYP2A6BCL2L1HDAC3HDAC4 | |
| SCHEMBL22684749 | 0.71 | MGLL (0.82) | MGLLCYP2A6BCL2L1HDAC3HDAC4 | |
| SCHEMBL15024948 | 0.69 | MGLL (0.55) | MGLLCYP2A6BCL2L1ERN1HDAC3 | |
| SCHEMBL8166709 | 0.68 | MGLL (0.74) | MGLLCYP2A6BCL2L1HDAC3HDAC4 | |
| SCHEMBL29629031 | 0.67 | CYP2A6 (1.00) | MGLLCYP2A6BCL2L1ERN1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-10-14 | — | — | US | disclosed |
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | BRCA1, BTD, BCHE | MGLL 1060/4885CYP2A6 754/4885BCL2L1 1826/4885 |
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | BRCA1, BTD, BCHE | MGLL 1060/4885CYP2A6 754/4885BCL2L1 1826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.