Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 8/20 | 0.52 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8261183 | 1.00 | REN (0.55) | RENACEF2ACE2CTRB1 | |
| SCHEMBL13241217 | 1.00 | REN (0.55) | RENACEF2ACE2CTRB1 | |
| SCHEMBL971479 | 1.00 | REN (0.55) | RENACEF2ACE2CTRB1 | |
| SCHEMBL8255495 | 1.00 | REN (0.55) | RENACEF2ACE2CTRB1 | |
| SCHEMBL2475863 | 1.00 | REN (0.55) | RENACEF2ACE2CTRB1 | |
| SCHEMBL8165627 | 1.00 | REN (0.55) | RENACEF2ACE2CTRB1 | |
| SCHEMBL8261170 | 1.00 | REN (0.55) | RENACEF2ACE2CTRB1 | |
| SCHEMBL8257154 | 0.96 | REN (0.52) | RENACEF2ACE2CTRB1 | |
| SCHEMBL30132290 | 0.94 | REN (0.54) | RENACEF2ACE2CTRB1 | |
| SCHEMBL13533688 | 0.92 | REN (0.55) | RENACEF2ACE2CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-10-14 | — | — | US | disclosed |
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | BRCA1, BTD, BCHE | REN 2554/4885ACE 2373/4885F2 2339/4885 |
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | BRCA1, BTD, BCHE | REN 2554/4885ACE 2373/4885F2 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.