Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 4/20 | 0.34 |
| ▸ | RASGRP3 | Q8IV61 | 4/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974571 | 0.84 | HDAC4 (0.33) | THRB | |
| SCHEMBL19978918 | 0.84 | HDAC4 (0.33) | THRB | |
| SCHEMBL19974567 | 0.83 | TBXAS1 (0.37) | TBXAS1NT5EDHODH | |
| SCHEMBL19974597 | 0.81 | NT5E (0.36) | TBXAS1NT5EDHODH | |
| SCHEMBL26558064 | 0.80 | GLA (0.34) | THRB | |
| SCHEMBL22700173 | 0.80 | GLA (0.35) | THRB | |
| SCHEMBL19974581 | 0.77 | GLA (0.33) | THRB | |
| SCHEMBL19979038 | 0.77 | GLA (0.33) | THRB | |
| SCHEMBL19978973 | 0.76 | GLA (0.32) | THRB | |
| SCHEMBL19974420 | 0.76 | GLA (0.32) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512860-B1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC (CA) | 2020-11-25 | — | — | EP | disclosed |