Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 13/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22700669 | 0.92 | CDK4 (0.44) | GPR6 | |
| SCHEMBL23196454 | 0.77 | SRPK1 (0.53) | GPR6ALDH1A1HPGDMAPT | |
| SCHEMBL22700679 | 0.72 | CDK4 (0.68) | GPR6MAPTKMT2A | |
| SCHEMBL24292436 | 0.69 | CDK4 (0.60) | ALDH1A1HPGDMAPTGAAKMT2A | |
| SCHEMBL12855741 | 0.69 | KDR (0.64) | ALDH1A1HPGDMAPTCYP2C9CYP2C19 | |
| SCHEMBL20198520 | 0.69 | NPSR1 (0.72) | ALDH1A1HPGDMAPTGAAKMT2A | |
| SCHEMBL23196345 | 0.67 | MAPT (0.52) | GPR6ALDH1A1HPGDMAPTGAA | |
| SCHEMBL16697303 | 0.64 | MAPT (0.64) | ALDH1A1HPGDMAPTGAAKMT2A | |
| SCHEMBL4453290 | 0.64 | MEN1 (0.69) | MAPTGAACYP2C9CYP2C19KMT2A | |
| SCHEMBL1786140 | 0.64 | MEN1 (0.69) | MAPTGAACYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020235672-A1 | PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE | 国立大学法人京都大学 (JP) | 2020-11-26 | — | — | WO | disclosed |