Geniposidic Acid

Geniposidic Acid

SCHEMBL227010

O=C(O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]2C(CO)=CC[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 7/20 0.70
▸ MAPT P10636 1/20 0.60
▸ PTPN2 P17706 1/20 0.49
▸ PTPN11 Q06124 1/20 0.49
▸ STAT3 P40763 4/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ixoside SCHEMBL29474997 0.90 MAPT (0.63) PTPN1MAPTSTAT3
Geniposide SCHEMBL28006822 0.89 PTPN1 (0.70) PTPN1MAPTSTAT3
Geniposide SCHEMBL21765150 0.89 PTPN1 (0.70) PTPN1MAPTSTAT3
Geniposide SCHEMBL16264978 0.89 PTPN1 (0.70) PTPN1MAPTSTAT3
Geniposide SCHEMBL17776267 0.89 PTPN1 (0.70) PTPN1MAPTSTAT3
SCHEMBL31228947 0.88 PTPN1 (0.57) PTPN1MAPT
SCHEMBL31338951 0.88 MAPT (0.63) PTPN1MAPTSTAT3
SCHEMBL29425885 0.88 MAPT (0.63) PTPN1MAPTSTAT3
Geniposidic Acid SCHEMBL6824308 0.87 PTPN1 (0.57) PTPN1MAPTPTPN2PTPN11STAT3
SCHEMBL30904657 0.86 PTPN1 (0.64) PTPN1MAPTSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005693-A Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis 河南中医药大学 2026-05-12 — — CN claimed
US-20260021152-A1 USE OF MALE FLOWER EXTRACT OF EUCOMMIA ULMOIDES OLIVER IN PREPARATION OF FOOD OR MEDICAMENT FOR RESISTING MUSCLE AGING UNIV ZHEJIANG (CN) 2026-01-22 — — US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 — — EP claimed
EP-4379068-B1 IRIDOID OR SECO-IRIDOID DERIVATIVES AND THEIR USE IN A TANNING PROCESS INSTITUT NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) 2025-06-04 — — EP claimed
CN-119868482-A Chinese herbal compound composition for treating middle-late diabetic nephropathy, preparation method and quality detection method thereof 江苏省中医院 2025-04-25 — — CN claimed
CN-119191273-B Nitrogen-doped biomass-based porous carbon material, and preparation method and application thereof 河北省科学院能源研究所 2025-02-18 — — CN claimed
CN-119191273-A Nitrogen-doped biomass-based porous carbon material, and preparation method and application thereof 河北省科学院能源研究所 2024-12-27 — — CN claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 — — WO claimed
US-12146869-B2 Methods and compositions for analyte quantification MATTERWORKS INC (US) 2024-11-19 — — US claimed
CN-118937532-A Quality control method of Chinese herbal compound containing radix rehmanniae Preparata and fructus Psoraleae and its application 湖南易能生物医药有限公司 2024-11-12 — — CN claimed
WO-2005046519-A1 DRUG-ELUTING BIODEGRADABLE STENT GP MEDICAL, INC. (US) 2005-05-26 — — WO claimed
US-20050019404-A1 delivering medical equipment having layers or zones containing drugs, to the target tissues for release of drugs; tissue-targeted therapy; drug delivery GP MEDICAL, INC. 2005-01-27 — — US claimed
CN-1091095-C Method of extracting the effective components from gettama leaf by using supercritical carbon dioxide GUTE GETTAMA DEV CO LTD ZUNYI (CN) 2002-09-18 — — CN claimed
WO-2001001996-A9 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS UNIV WESTERN AUSTRALIA (AU) 2002-09-12 — — WO claimed
WO-2001001996-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS UNIVERSITY OF WESTERN AUSTRALIA (AU) 2001-01-11 — — WO claimed
CN-1241560-A Method of extracting the effective components from gettama leaf by using supercritical carbon dioxide GUTE GETTAMA DEV CO LTD ZUNYI (CN) 2000-01-19 — — CN claimed
WO-1996010408-A1 CARDIOACTIVE COMPOUNDS ISOLATED FROM WOODY PERENNIALS THE EXECUTIVE DIRECTOR OF THE WESTERN AUSTRALIAN DEPARTMENT OF CONSERVATION AND LAND MANAGEMENT (AU) 1996-04-11 — — WO claimed
US-5270446-A Crosslinking primary amine compound with iridoid compound SUNTORY LIMITED (JP) 1993-12-14 — — US claimed
US-5078750-A HAIR DYEING BY IRIDOID GLYCOSIDES AND AGLYCONS THEREOF TOKIWA KANPO PHARMACEUTICAL CO., LTD. (JP) 1992-01-07 — — US claimed
EP-0440494-A2 Hair dyeing TOKIWA KANPO PHARMACEUTICAL CO., LTD. (JP) 1991-08-07 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021152-A1 USE OF MALE FLOWER EXTRACT OF EUCOMMIA ULMOIDES OLIVER IN PREPARATION OF FOOD OR MEDICAMENT FOR RESISTING MUSCLE AGING FIS1, OPA1, TFAM PTPN1 4494/4885MAPT 1797/4885PTPN2 4597/4885
US-20050019404-A1 delivering medical equipment having layers or zones containing drugs, to the target tissues for release of drugs; tissue-targeted therapy; drug delivery PLAUR, ABCB1, MATR3 PTPN1 4001/4885MAPT 2706/4885PTPN2 4289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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