Sugi Predict

Sugi Predict / Compounds / SCHEMBL22701003

SCHEMBL22701003

SCHEMBL22701003

SCCCc1ccccc1CCCS

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 5/20 0.41
▸ IDO1 P14902 2/20 0.40
▸ HDAC3 O15379 2/20 0.39
▸ HDAC4 P56524 2/20 0.39
▸ HDAC1 Q13547 2/20 0.39
▸ HDAC7 Q8WUI4 2/20 0.39
▸ HDAC2 Q92769 2/20 0.39
▸ HDAC10 Q969S8 2/20 0.39
▸ HDAC11 Q96DB2 2/20 0.39
▸ HDAC8 Q9BY41 2/20 0.39
▸ HDAC6 Q9UBN7 2/20 0.39
▸ HDAC9 Q9UKV0 2/20 0.39
▸ HDAC5 Q9UQL6 2/20 0.39
▸ LIPG Q9Y5X9 1/20 0.35
▸ HTR2A P28223 1/20 0.34
▸ MPO P05164 1/20 0.34
▸ SLC6A4 P31645 1/20 0.34
▸ MMP3 P08254 2/20 0.34
▸ MMP8 P22894 2/20 0.34
▸ MMP13 P45452 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10540048 0.83 TAAR1 (0.56) MPOSLC6A4TAAR1
SCHEMBL17933790 0.83 TAAR1 (0.56) FOLH1TAAR1
SCHEMBL15327777 0.82 HDAC3 (0.34) FOLH1IDO1HDAC3HDAC4HDAC1
SCHEMBL29362123 0.81 FOLH1 (0.56) FOLH1IDO1HTR2ATAAR1
SCHEMBL330664 0.81 FOLH1 (0.56) FOLH1IDO1HTR2ATAAR1
SCHEMBL129738 0.79 CYP1A2 (0.50) —
SCHEMBL3790959 0.79 FOLH1 (0.54) FOLH1
SCHEMBL22367628 0.78 HRH1 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL17750799 0.78 KDM4E (0.38) FOLH1LIPGTAAR1
SCHEMBL29507667 0.78 HRH1 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds SHIKOKU CHEMICALS CORPORATION (JP) 2023-11-07 — — US disclosed
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds SHIKOKU CHEMICALS CORPORATION (JP) 2023-11-07 — — US disclosed
US-20200369606-A1 THIOL COMPOUNDS, SYNTHESIS METHOD THEREFOR, AND UTILIZATION OF SAID THIOL COMPOUNDS SHIKOKU CHEMICALS CORPORATION (JP) 2020-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200369606-A1 THIOL COMPOUNDS, SYNTHESIS METHOD THEREFOR, AND UTILIZATION OF SAID THIOL COMPOUNDS TMT1A, CTH, SLC7A11 FOLH1 710/4885IDO1 2702/4885HDAC3 4544/4885
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds TMT1A, CTH, SLC7A11 FOLH1 710/4885IDO1 2702/4885HDAC3 4544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.