Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | QPCT | Q16769 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22102730 | 0.94 | MAPKAPK2 (0.36) | GAAMAPKAPK2KMT2ASMN1; SMN2QPCT | |
| SCHEMBL22701347 | 0.87 | MEN1 (0.32) | GAAKMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL20268996 | 0.86 | MEN1 (0.40) | KMT2ASMN1; SMN2QPCTMAPTHTT | |
| SCHEMBL20288337 | 0.84 | MEN1 (0.39) | KMT2ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL20267791 | 0.82 | MAPT (0.36) | KMT2ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL22102729 | 0.81 | MAPT (0.36) | GAAKMT2ASMN1; SMN2QPCTMAPT | |
| SCHEMBL20280485 | 0.80 | MEN1 (0.35) | KMT2ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL20267798 | 0.80 | MEN1 (0.35) | GAAKMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL20280488 | 0.78 | MEN1 (0.34) | KMT2ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL22701334 | 0.75 | TSHR (0.51) | GAAKMT2ASMN1; SMN2CTDSP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | disclosed |