Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14304175 | 0.84 | KDM4E (0.54) | KDM4EPOLBTSHRTACR1IDO1 | |
| SCHEMBL27382470 | 0.83 | TSHR (0.52) | KDM4EPOLBTSHRTACR1IDO1 | |
| SCHEMBL18618591 | 0.83 | KDM4E (0.57) | KDM4EPOLBTSHRTACR1IDO1 | |
| SCHEMBL3334160 | 0.80 | KDM4E (0.53) | KDM4EPOLBTSHRTACR1CYP1A2 | |
| SCHEMBL16093891 | 0.80 | TSHR (0.52) | KDM4EPOLBTSHRTACR1CYP1A2 | |
| SCHEMBL13176618 | 0.80 | KDM4E (0.50) | KDM4EPOLBTSHRTACR1TAAR1 | |
| SCHEMBL15663590 | 0.79 | KDM4E (0.56) | KDM4EPOLBTSHRTACR1CYP1A2 | |
| SCHEMBL19621150 | 0.78 | TSHR (0.54) | KDM4EPOLBTSHRTACR1IDO1 | |
| SCHEMBL24219655 | 0.78 | POLB (0.47) | KDM4EPOLBTSHRTACR1CA1 | |
| SCHEMBL18630911 | 0.77 | KDM4E (0.50) | KDM4EPOLBTSHRTACR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234208-A1 | PROCESS FOR THE PREPARATION OF GALNAC PHOSPHORAMIDITE EPIMERS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-11-26 | — | — | WO | disclosed |