Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149158 | 0.87 | KIF11 (0.64) | KIF11TSHRCYP11B1CYP11B2KCNH2 | |
| SCHEMBL11814132 | 0.80 | TSHR (0.48) | KIF11TSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11602752 | 0.77 | KIF11 (0.54) | KIF11TSHRCYP11B1CYP11B2KCNH2 | |
| SCHEMBL3146564 | 0.75 | KIF11 (0.52) | KIF11CYP11B1CYP11B2CYP1A2KCNH2 | |
| SCHEMBL27656873 | 0.74 | KIF11 (0.62) | KIF11TSHRCYP11B1CYP11B2KCNH2 | |
| SCHEMBL28248374 | 0.73 | KIF11 (0.61) | KIF11TSHRCYP11B1CYP11B2KCNH2 | |
| SCHEMBL532102 | 0.72 | KIF11 (0.54) | KIF11TSHRCYP11B1CYP11B2KCNH2 | |
| SCHEMBL10932721 | 0.72 | KIF11 (0.54) | KIF11TSHRCYP11B1CYP11B2KCNH2 | |
| SCHEMBL7092683 | 0.72 | KIF11 (0.54) | KIF11TSHRCYP11B1CYP11B2KCNH2 | |
| SCHEMBL10932723 | 0.72 | KIF11 (0.54) | KIF11TSHRCYP11B1CYP11B2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369828-A1 | PROCESS FOR PREPARING POLYCARBONTE AND CATALYTIC SYSTEM USED | ENI S.P.A. (IT) | 2020-11-26 | — | — | US | disclosed |