Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704484 | 0.92 | POLB (0.31) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22704373 | 0.92 | KDM4E (0.34) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22704500 | 0.92 | POLB (0.31) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22704366 | 0.92 | POLB (0.31) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL24294376 | 0.88 | POLB (0.31) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22704499 | 0.88 | POLB (0.31) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22704389 | 0.88 | KDM4E (0.36) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL26707596 | 0.86 | SIGMAR1 (0.31) | — | |
| SCHEMBL24294685 | 0.84 | SIGMAR1 (0.33) | — | |
| SCHEMBL24294542 | 0.84 | CARM1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971176-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | Hinova Pharmaceuticals Inc. (CN) | 2022-03-23 | — | — | EP | disclosed |
| WO-2020233512-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | 成都海创药业有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |