Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12131647 | 1.00 | CHRM2 (0.36) | CHRM2DRD2L3MBTL3CHRM4CHRM5 | |
| SCHEMBL14253891 | 0.94 | CYP2D6 (0.33) | CHRM2DRD2L3MBTL3 | |
| SCHEMBL10735229 | 0.86 | RAD52 (0.35) | CHRM2L3MBTL3 | |
| SCHEMBL17662649 | 0.86 | — | — | |
| SCHEMBL14962056 | 0.86 | — | — | |
| SCHEMBL17662672 | 0.86 | — | — | |
| SCHEMBL20384112 | 0.85 | L3MBTL3 (0.38) | CHRM2DRD2L3MBTL3CHRM4CHRM5 | |
| SCHEMBL22704387 | 0.85 | L3MBTL3 (0.38) | CHRM2DRD2L3MBTL3CHRM4CHRM5 | |
| SCHEMBL20384067 | 0.85 | CHRM2 (0.39) | CHRM2DRD2L3MBTL3CHRM4CHRM5 | |
| SCHEMBL22704369 | 0.85 | CHRM2 (0.39) | CHRM2DRD2L3MBTL3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971176-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | Hinova Pharmaceuticals Inc. (CN) | 2022-03-23 | — | — | EP | disclosed |
| WO-2020233512-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | 成都海创药业有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |