Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704536 | 0.88 | KDM4E (0.34) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22704533 | 0.88 | POLB (0.31) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22704503 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL24294347 | 0.85 | — | — | |
| SCHEMBL19501864 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22704535 | 0.82 | POLB (0.30) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL25050066 | 0.81 | KDM1A (0.31) | — | |
| SCHEMBL20103945 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22704481 | 0.79 | KDM4E (0.34) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL14267884 | 0.79 | HTT (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971176-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | Hinova Pharmaceuticals Inc. (CN) | 2022-03-23 | — | — | EP | disclosed |
| WO-2020233512-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | 成都海创药业有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |