⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704696 | 0.81 | PDE4A (0.31) | — | |
| SCHEMBL12222444 | 0.74 | STING1 (0.52) | — | |
| SCHEMBL12352439 | 0.74 | STING1 (0.52) | — | |
| SCHEMBL12595500 | 0.74 | STING1 (0.52) | — | |
| SCHEMBL8624094 | 0.74 | STING1 (0.52) | — | |
| SCHEMBL12729578 | 0.74 | STING1 (0.52) | — | |
| SCHEMBL17772331 | 0.74 | STING1 (0.52) | — | |
| SCHEMBL17106799 | 0.73 | STING1 (0.36) | — | |
| SCHEMBL17106677 | 0.73 | DOT1L (0.31) | — | |
| SCHEMBL17106670 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20200369711-A1 | MODIFIED CYCLIC DINUCLEOSIDE COMPOUNDS AS STING MODULATORS | ALIGOS THERAPEUTICS, INC. | 2020-11-26 | — | — | US | disclosed |