Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 3/20 | 0.52 |
| ▸ | ADA | P00813 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 2/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 5/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12595500 | 1.00 | STING1 (0.52) | STING1ADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL12352439 | 1.00 | STING1 (0.52) | STING1ADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL12222444 | 1.00 | STING1 (0.52) | STING1ADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL17772331 | 1.00 | STING1 (0.52) | STING1ADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL12729578 | 1.00 | STING1 (0.52) | STING1ADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL6899409 | 0.85 | PDE4D (0.49) | STING1TP53ADORA2AADORA3ADORA1 | |
| SCHEMBL16271095 | 0.85 | STING1 (0.38) | STING1ADAADORA3 | |
| SCHEMBL7894271 | 0.85 | AHCY (0.46) | STING1TP53AHCYADORA2AADORA3 | |
| SCHEMBL21049964 | 0.82 | STING1 (0.49) | STING1MAPK1ALDH1A1 | |
| SCHEMBL17037317 | 0.82 | STING1 (0.49) | STING1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756704-A | Nucleosides and nucleoside derivatives containing enzymatically cleavable protecting groups | BOEHRINGER MANNHEIM GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5677441-A | Nucleosides, nucleotides and oligonucleotides containing enzymatically cleavable protecting groups | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| EP-0649855-A1 | Use of nucleosides and nucleoside derivatives with enzymatically cleavable protecting groupes in the synthesis of oligonucleotiden | Roche Diagnostics GmbH (DE) | 1995-04-26 | — | — | EP | disclosed |