SCHEMBL22705192

SCHEMBL22705192

N#Cc1cc(-n2c3ccccc3c3cc(-c4ccccn4)ccc32)nc(-n2c3ccccc3c3cc(-c4ccccn4)ccc32)c1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 14/20 0.42
NPY5R Q15761 1/20 0.41
TGFBR1 P36897 1/20 0.38
PTGER4 P35408 1/20 0.37
METAP2 P50579 1/20 0.37
METAP1 P53582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22705188 0.96 GRM5 (0.45) GRM5METAP2METAP1
SCHEMBL22454895 0.84 GRM5 (0.44) GRM5NPY5RTGFBR1PTGER4METAP2
SCHEMBL13912328 0.82 PTGER4 (0.46) PTGER4METAP2
SCHEMBL22705228 0.81 PTGER4 (0.44) PTGER4
SCHEMBL23343985 0.81 NPY5R (0.43) GRM5NPY5RTGFBR1METAP2
SCHEMBL21022645 0.80 GRM5 (0.46) GRM5
SCHEMBL29029993 0.80 IRAK4 (0.43) NPY5RMETAP2METAP1
SCHEMBL25837041 0.80 NPY5R (0.40) GRM5NPY5RTGFBR1METAP2
SCHEMBL25837042 0.80 NPY5R (0.40) GRM5NPY5RTGFBR1METAP2
SCHEMBL26940636 0.78 KDM4E (0.40) PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373509-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-26 US disclosed