SCHEMBL22705756

SCHEMBL22705756

c1ccc(-c2cccc3ccc(-c4c5cccc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)c5cc5c(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)cccc45)cc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
KMT2A Q03164 2/20 0.36
MCL1 Q07820 1/20 0.35
ACMSD Q8TDX5 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
PTGER4 P35408 1/20 0.34
TNF P01375 1/20 0.34
MAPK14 Q16539 1/20 0.34
NTSR1 P30989 2/20 0.33
IL1R1 P14778 1/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
TLR4 O00206 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22705747 0.95 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AMCL1
SCHEMBL22708161 0.93 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AMCL1
SCHEMBL22708171 0.92 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMCL1
SCHEMBL22706591 0.92 KDM4E (0.43) L3MBTL1KDM4EATMKMT2AMCL1
SCHEMBL22705680 0.91 KDM4E (0.45) L3MBTL1KDM4EATMKMT2AMCL1
SCHEMBL22706327 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL22706418 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2AMCL1
SCHEMBL22706385 0.90 KDM4E (0.44) L3MBTL1KDM4EATMKMT2AMCL1
SCHEMBL22707262 0.90 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2ACA12
SCHEMBL17917508 0.90 KDM4E (0.49) L3MBTL1KDM4EATMKMT2AMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed