⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523200 | 0.79 | — | — | |
| SCHEMBL78894 | 0.76 | — | — | |
| SCHEMBL2870637 | 0.74 | — | — | |
| SCHEMBL2869233 | 0.74 | — | — | |
| SCHEMBL122361 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL7977630 | 0.62 | — | — | |
| Bromide SCHEMBL17434706 | 0.62 | — | — | |
| SCHEMBL778160 | 0.62 | — | — | |
| Piperazine SCHEMBL3888557 | 0.59 | HIF1A (0.33) | — | |
| SCHEMBL237047 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5390 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785123-A | Novel BTK inhibitor and application thereof | 乳源东阳光药业有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | claimed |
| US-9630934-B2 | Fumarate compounds, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2017-04-25 | — | — | US | claimed |
| EP-2763993-B1 | HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE | BAYER IP GMBH (DE) | 2017-04-19 | — | — | EP | claimed |
| EP-2488510-B1 | Amides and thioamides as pest control agents | BAYER IP GMBH (DE) | 2017-03-29 | — | — | EP | claimed |
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | claimed |
| US-20160229819-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2016-08-11 | — | — | US | claimed |
| EP-1953145-B1 | HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON 11-B-HYDROXYSTEROID DEHYDROGENASE TYPE I | SHIONOGI & CO (JP) | 2015-11-04 | — | — | EP | claimed |
| WO-2015107133-A1 | QUINOLINE DERIVATIVES AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2015-07-23 | — | — | WO | claimed |
| US-5955481-A | Pyridine type thiazolidines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-21 | — | — | US | claimed |
| US-5935968-A | ADMINISTERING ANDROSTENE DERIVATIVE 5-ALPHA REDUCTASE INHIBITOR | MERCK & CO., INC. (US) | 1999-08-10 | — | — | US | claimed |
| WO-1998046571-A1 | METHODS FOR SYNTHESIZING 2-SUBSTITUTED IMIDAZOLES | SEPRACOR INC. (US) | 1998-10-22 | — | — | WO | claimed |
| US-5817823-A | ALKYLATION OF AN IMIDAZOLE COMPOUND; COUPLING WITH NUCLEOPHILIC COMPOUND | SEPRACOR INC. (US) | 1998-10-06 | — | — | US | claimed |
| WO-1998041509-A1 | METHODS AND COMPOSITIONS FOR TREATING POLYCYSTIC OVARY SYNDROME | MERCK & CO., INC. (US) | 1998-09-24 | — | — | WO | claimed |
| EP-0686152-B1 | ORTHO-SUBSTITUTED 2-METHOXYIMINOPHENYLACETIC ACID METHYLAMIDES | BASF AG (DE) | 1997-05-02 | — | — | EP | claimed |
| CN-1144526-A | Thiazolidines and oxazolidines substituted by pyridine ring and their use a hypoglycemic agents | NISSAN CHEMICAL IND LTD (JP) | 1997-03-05 | — | — | CN | claimed |
| EP-0751944-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-01-08 | — | — | EP | claimed |
| WO-1995026347-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-05 | — | — | WO | claimed |
| US-4200628-A | ANTIBIOTICS, BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1980-04-29 | — | — | US | claimed |