⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870637 | 1.00 | — | — | |
| SCHEMBL78894 | 0.97 | — | — | |
| SCHEMBL20424 | 0.88 | — | — | |
| SCHEMBL22706 | 0.74 | — | — | |
| SCHEMBL1089494 | 0.72 | — | — | |
| SCHEMBL1088460 | 0.72 | — | — | |
| SCHEMBL1088459 | 0.72 | — | — | |
| SCHEMBL779806 | 0.71 | — | — | |
| SCHEMBL194674 | 0.69 | — | — | |
| SCHEMBL5010068 | 0.69 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4638000-A | HYPOTENSIVES, ANGIOTENSIN INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-01-20 | — | — | US | claimed |
| US-4548932-A | ANGIOTENSIN INHIBITOR, HYPOTENSIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-22 | — | — | US | claimed |
| EP-3408258-A1 | ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE | Abbvie Deutschland GmbH & Co. KG (DE) | 2018-12-05 | — | — | EP | disclosed |
| WO-2017157929-A1 | QUINOLINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO THE MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-09-21 | — | — | WO | disclosed |
| WO-2017129796-A1 | ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-08-03 | — | — | WO | disclosed |
| US-8592420-B2 | Method of treating an anxiety disorder | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-11-26 | — | — | US | disclosed |
| US-20120232089-A1 | METHOD OF TREATING AN ANXIETY DISORDER | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-8202869-B2 | Method of treating an anxiety disorder | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-06-19 | — | — | US | disclosed |
| US-7851478-B2 | Agent for preventing and/or treating movement disorder | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-12-14 | — | — | US | disclosed |
| EP-2258372-A1 | A2A antagonists for use in the treatment of motor disorders | Kyowa Hakko Kirin Co., Ltd. (JP) | 2010-12-08 | — | — | EP | disclosed |
| US-20090105277-A1 | AGENT FOR PREVENTING AND/OR TREATING MOVEMENT DISORDER | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1736474-A1 | PIPERIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-20060281770-A1 | Method of treating an anxiety disorder | KYOWA HAKKO KOGYO CO. LTD (JP) | 2006-12-14 | — | — | US | disclosed |
| EP-1631294-A1 | A METHOD OF TREATING AN ANXIETY DISORDER | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004108137-A1 | A METHOD OF TREATING AN ANXIETY DISORDER | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
| US-4739066-A | HYPOTENSIVE AGENTS, ANGIOTENSIN INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4638000-A | HYPOTENSIVES, ANGIOTENSIN INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-01-20 | — | — | US | disclosed |
| US-4591458-A | ENZYME INHIBITORS; HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-05-27 | — | — | US | disclosed |
| US-4548932-A | ANGIOTENSIN INHIBITOR, HYPOTENSIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0135349-A1 | Condensed seven-membered ring compounds and their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-03-27 | — | — | EP | disclosed |