SCHEMBL22706284

SCHEMBL22706284

Cn1c2ccccc2c2c(-c3cccc4c(-c5cc(-c6ccccc6)cc6ccccc56)c5cccc(-c6cccc7c6c6ccccc6n7C)c5cc34)cccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.37
KMT2A Q03164 4/20 0.36
CASP1 P29466 2/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
GALK1 P51570 1/20 0.36
BLM P54132 1/20 0.36
CASP7 P55210 1/20 0.36
SAE1 Q9UBE0 1/20 0.36
UBA2 Q9UBT2 1/20 0.36
TOP2A P11388 2/20 0.36
GPR3 P46089 1/20 0.35
HPGD P15428 3/20 0.35
MAPT P10636 2/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22706715 0.91 HSD17B10 (0.43) HSD17B10KMT2ACASP1GAAPKM
SCHEMBL22706965 0.87 HSD17B10 (0.39) HSD17B10KMT2ACASP1GAAPKM
SCHEMBL22706286 0.86 ALKBH5 (0.40) HSD17B10KMT2ACASP1GAAPKM
SCHEMBL22707638 0.85 HSD17B10 (0.42) HSD17B10KMT2ACASP1GAAPKM
SCHEMBL22705861 0.85 HSD17B10 (0.46) HSD17B10KMT2ACASP1GAAPKM
SCHEMBL22707071 0.85 HSD17B10 (0.46) HSD17B10KMT2ATOP2AGPR3HPGD
SCHEMBL22707728 0.85 HSD17B10 (0.42) HSD17B10KMT2ACASP1CASP7TOP2A
SCHEMBL22706676 0.85 HSD17B10 (0.44) HSD17B10KMT2ACASP1CASP7TOP2A
SCHEMBL22706521 0.84 HSD17B10 (0.41) HSD17B10KMT2ACASP1GALK1BLM
SCHEMBL22706510 0.84 HSD17B10 (0.41) HSD17B10KMT2AGPR3HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed