SCHEMBL22706289

SCHEMBL22706289

Cn1c2ccccc2c2cccc(-c3cccc4c(-c5ccc(-c6ccccc6)c6ccccc56)c5cccc(-c6cccc7c8ccccc8n(C)c67)c5cc34)c21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.45
FTO Q9C0B1 1/20 0.45
HSD17B10 Q99714 3/20 0.44
HSP90AA1 P07900 1/20 0.44
IDO1 P14902 1/20 0.44
GPR3 P46089 1/20 0.40
HPGD P15428 2/20 0.38
LMNA P02545 2/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPK14 Q16539 1/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 2/20 0.35
MAPT P10636 1/20 0.35
NTRK1 P04629 2/20 0.34
CYP2C19 P33261 1/20 0.34
CDC25A P30304 1/20 0.34
CDC25C P30307 1/20 0.34
HSD11B1 P28845 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22707069 0.99 ALKBH5 (0.46) ALKBH5FTOHSD17B10HSP90AA1IDO1
SCHEMBL22705860 0.93 ALKBH5 (0.46) ALKBH5FTOHSD17B10HSP90AA1IDO1
SCHEMBL22706516 0.90 ALKBH5 (0.46) ALKBH5FTOHSD17B10HSP90AA1IDO1
SCHEMBL22706778 0.90 ALKBH5 (0.49) ALKBH5FTOHSD17B10HSP90AA1IDO1
SCHEMBL22706866 0.90 ALKBH5 (0.41) ALKBH5FTOHSD17B10HSP90AA1IDO1
SCHEMBL22707670 0.90 ALKBH5 (0.41) ALKBH5FTOHSD17B10HSP90AA1IDO1
SCHEMBL20334569 0.89 ALKBH5 (0.53) ALKBH5FTOHSD17B10HSP90AA1IDO1
SCHEMBL22706717 0.88 ALKBH5 (0.42) ALKBH5FTOHSD17B10HSP90AA1IDO1
SCHEMBL22706671 0.88 ALKBH5 (0.46) ALKBH5FTOHSD17B10HSP90AA1IDO1
SCHEMBL22706682 0.86 ALKBH5 (0.45) ALKBH5FTOHSD17B10HSP90AA1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed