SCHEMBL22706296

SCHEMBL22706296

c1ccc(-n2c3ccccc3c3c(-c4cccc5c(-c6ccc7ccccc7c6)c6cccc(-c7cccc8c7c7ccccc7n8-c7ccccc7)c6cc45)cccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
PIM1 P11309 2/20 0.33
GPR84 Q9NQS5 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
TSHR P16473 2/20 0.33
HIF1A Q16665 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SOS1 Q07889 1/20 0.33
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22706239 0.96 L3MBTL1 (0.40) L3MBTL1KDM4EATMPIM1GPR84
SCHEMBL22706774 0.94 KDM4E (0.40) L3MBTL1KDM4EATMPIM1GPR84
SCHEMBL22707261 0.94 L3MBTL1 (0.40) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL22706376 0.93 L3MBTL1 (0.39) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL24292875 0.93 KDM4E (0.42) L3MBTL1KDM4EATMPIM1GPR84
SCHEMBL22705753 0.90 L3MBTL1 (0.38) L3MBTL1KDM4EATMKMT2AHDAC8
SCHEMBL22705767 0.90 L3MBTL1 (0.38) L3MBTL1KDM4EATMKMT2AHDAC8
SCHEMBL24173713 0.89 KDM4E (0.40) L3MBTL1KDM4EATMGPR84KMT2A
SCHEMBL22706388 0.89 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2ATSHR
SCHEMBL22706222 0.88 L3MBTL1 (0.39) L3MBTL1KDM4EATMKMT2AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed