SCHEMBL2270719

SCHEMBL2270719

COCC(c1ccc(F)cc1)C(COC)c1ccc(F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
IDO1 P14902 2/20 0.41
TDO2 P48775 2/20 0.41
CYP19A1 P11511 2/20 0.40
SIGMAR1 Q99720 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HTT P42858 2/20 0.37
MAPT P10636 1/20 0.37
MITF O75030 1/20 0.36
LMNA P02545 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
GPR35 Q9HC97 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
XBP1 P17861 1/20 0.36
MAPK1 P28482 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17084072 0.90 AOC3 (0.43) AOC3SLC6A2SLC6A4SLC6A3IDO1
SCHEMBL15445213 0.90 AOC3 (0.43) AOC3SLC6A2SLC6A4SLC6A3IDO1
SCHEMBL25704721 0.90 AOC3 (0.43) AOC3SLC6A2SLC6A4SLC6A3IDO1
SCHEMBL20459581 0.85 SLC6A2 (0.37) AOC3SLC6A2SLC6A4SLC6A3IDO1
SCHEMBL812512 0.82 AOC3 (0.43) AOC3SLC6A2SLC6A4SLC6A3IDO1
SCHEMBL16224877 0.80 AOC3 (0.42) AOC3SLC6A2SLC6A4SLC6A3IDO1
SCHEMBL19493681 0.80 AOC3 (0.42) AOC3SLC6A2SLC6A4SLC6A3IDO1
SCHEMBL17086661 0.80 AOC3 (0.42) AOC3SLC6A2SLC6A4SLC6A3IDO1
SCHEMBL17086659 0.80 AOC3 (0.42) AOC3SLC6A2SLC6A4SLC6A3IDO1
SCHEMBL4578371 0.78 AOC3 (0.44) AOC3SLC6A2SLC6A4SLC6A3IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110196103-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST MITSUI CHEMICALS, INC. (US) 2011-08-11 US disclosed
US-7767313-B2 Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer MITSUI CHEMICALS, INC. (JP) 2010-08-03 US disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
US-7728078-B2 Blend of a polypropylene and a elastomeric copolymer of 60-90 mol % propylene units and 10- 40 mol % of 1-butene units; sheets and films with excellent flexibility and impact resistance as well as sufficient heat resistance and low-temperature heat-sealability MITSUI CHEMICALS, INC. (JP) 2010-06-01 US disclosed
US-7678934-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-03-16 US disclosed
EP-1985638-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-02-17 EP disclosed
EP-1647575-B1 POLYPROPYLENE RESIN COMPOSITION PRIME POLYMER CO LTD (JP) 2009-07-29 EP disclosed
EP-1270647-B1 BRANCHED POLYOLEFIN, PROCESS FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION CONTAINING BRANCHED POLYOLEFIN MITSUI CHEMICALS INC (JP) 2009-07-01 EP disclosed
US-20090043050-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2009-02-12 US disclosed
US-7488789-B2 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2009-02-10 US disclosed
US-5278210-A Process for the preparation of stabilized polyolefins and products obtained therefrom HIMONT INCORPORATED (US) 1994-01-11 US disclosed
US-5122492-A Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide HIMONT INCORPORATED (US) 1992-06-16 US disclosed
EP-0452156-A2 Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst and method of olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
CN-1052681-A The catalyst component of olefinic polymerization and catalyzer HIMONT INC (US) 1991-07-03 CN disclosed
EP-0434082-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-06-26 EP disclosed
EP-0423786-A2 Polymetallic catalysts, method of preparing and polymers produced thereby MONTELL NORTH AMERICA INC. (US) 1991-04-24 EP disclosed
US-4978648-A Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization HIMONT INCORPORATED (US) 1990-12-18 US disclosed
US-4971937-A COORDINATION CATALYSTS OF TITANIUM HALIDES, MAGNESIUM HALIDES AND DI OR POLYETHER COMPOUNDS HIMONT INCORPORATED (US) 1990-11-20 US disclosed
EP-0362705-A2 Catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-11 EP disclosed
EP-0361494-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-04 EP disclosed