SCHEMBL22707398

SCHEMBL22707398

c1ccc(-c2cc(-c3c4cccc(-c5cccc6c7cccc8c9ccccc9n(c56)c87)c4cc4c(-c5cccc6c7cccc8c9ccccc9n(c56)c87)cccc34)cc3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.38
KMT2A Q03164 5/20 0.38
MEN1 O00255 4/20 0.38
MAPT P10636 3/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
MPI P34949 1/20 0.38
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
HSD17B10 Q99714 2/20 0.33
RECQL P46063 1/20 0.32
PLEC Q15149 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GPR84 Q9NQS5 2/20 0.32
TSHR P16473 1/20 0.32
FLT3 P36888 1/20 0.31
CDC25B P30305 1/20 0.31
POLB P06746 1/20 0.31
HTT P42858 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22707562 0.90 KDM4E (0.33) KDM4EKMT2AMEN1MAPTALDH1A1
SCHEMBL22707392 0.90 KDM4E (0.36) KDM4EKMT2AMEN1MAPTALDH1A1
SCHEMBL22707555 0.87 KDM4E (0.36) KDM4EKMT2AMEN1MAPTALDH1A1
SCHEMBL22706988 0.87 HSD17B10 (0.43) KDM4EKMT2AMEN1MAPTALDH1A1
SCHEMBL22707397 0.86 ALDH1A1 (0.35) KDM4EKMT2AMEN1MAPTALDH1A1
SCHEMBL22705723 0.86 KDM4E (0.39) KDM4EKMT2AMEN1MAPTALDH1A1
SCHEMBL22706186 0.86 KDM4E (0.35) KDM4EKMT2AMEN1MAPTALDH1A1
SCHEMBL22707929 0.86 KDM4E (0.35) KDM4EKMT2AMEN1MAPTALDH1A1
SCHEMBL22706150 0.84 KDM4E (0.35) KDM4EKMT2AMEN1MAPTALDH1A1
SCHEMBL22707157 0.84 KDM4E (0.36) KDM4EKMT2AMEN1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed