Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402472 | 0.93 | MEN1 (0.65) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3354717 | 0.92 | HTT (0.71) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20382958 | 0.87 | HTT (0.71) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8102028 | 0.86 | HTT (0.70) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3289112 | 0.86 | HTT (0.70) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13060127 | 0.86 | HTT (0.70) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6327211 | 0.85 | MEN1 (0.68) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL30982687 | 0.85 | MEN1 (0.68) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL30982572 | 0.85 | MEN1 (0.68) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8108601 | 0.85 | HTT (0.68) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110200536-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110200536-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | TSPO, PML, AIP | HTT 410/4885SMN1; SMN2 2492/4885MEN1 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.