SCHEMBL2270798

SCHEMBL2270798

c1cn2c(n1)N=NC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10866570 0.67
SCHEMBL6560305 0.67
SCHEMBL2015423 0.64
SCHEMBL73223 0.62
SCHEMBL868737 0.62
SCHEMBL17459222 0.61 ADORA3 (0.32)
SCHEMBL30035677 0.61
SCHEMBL14974460 0.60
SCHEMBL30423920 0.58
SCHEMBL10378076 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288123-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-10-30 US claimed
WO-2007071686-A1 COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER L'ORÉAL (FR) 2007-06-28 WO claimed
US-20060042024-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof NOXELL CORPORATION 2006-03-02 US claimed
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses L'OREAL (FR) 2004-11-25 US claimed
EP-1428510-A1 Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use L'OREAL (FR) 2004-06-16 EP claimed
EP-0893985-B1 KERATIN FIBRE DYE COMPOSITIONS CONTAINING IMIDAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD OREAL (FR) 2000-04-12 EP claimed
US-12012467-B2 Small molecule DCN1 inhibitors and therapeutic methods using the same REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-06-18 US disclosed
CN-110740996-B Covalent small molecule DCN1 inhibitors and methods of treatment using the same 密执安大学评议会 2024-01-09 CN disclosed
EP-3609876-B1 COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME UNIV MICHIGAN REGENTS (US) 2022-03-30 EP disclosed
US-20200109167-A1 SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME UNIV MICHIGAN REGENTS (US) 2020-04-09 US disclosed
EP-3609876-A1 COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME The Regents of The University of Michigan (US) 2020-02-19 EP disclosed
EP-3601245-A1 SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME The Regents of The University of Michigan (US) 2020-02-05 EP disclosed
WO-2018191199-A1 COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2018-10-18 WO disclosed
EP-0740206-B1 Photographic elements containing magenta dye forming couplers and fade reducing compounds EASTMAN KODAK CO (US) 1998-04-01 EP disclosed
EP-0740205-A1 Photographic elements containing magenta dye forming couplers and fade reducing compounds--I EASTMAN KODAK COMPANY (US) 1996-10-30 EP disclosed
EP-0740204-A1 Photographic elements containing magenta dye forming couplers and fade reducing compounds--N EASTMAN KODAK COMPANY (US) 1996-10-30 EP disclosed
EP-0740206-A1 Photographic elements containing magenta dye forming couplers and fade reducing compounds EASTMAN KODAK COMPANY (US) 1996-10-30 EP disclosed
US-5565312-A LOW FADING ON EXPOSURE TO LIGHT EASTMAN KODAK COMPANY (US) 1996-10-15 US disclosed
US-5561037-A LOW FADING ON EXPOSURE TO LIGHT EASTMAN KODAK COMPANY (US) 1996-10-01 US disclosed
US-5424179-A Photographic element with a cyclic azole coupler having a saccharin substituent EASTMAN KODAK COMPANY (US) 1995-06-13 US disclosed