Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269118 | 0.87 | HRH3 (0.50) | HRH3HRH1HTR2CKCNH2MCHR1 | |
| SCHEMBL1790863 | 0.84 | PRKAB2 (0.56) | HRH3HRH1ADRA1A | |
| SCHEMBL1790797 | 0.83 | HRH3 (0.55) | HRH3HRH1MAPTMAPK1 | |
| SCHEMBL12418545 | 0.79 | HRH3 (0.51) | HRH3HRH1MAPTMAPK1KDM2B | |
| SCHEMBL12418544 | 0.79 | HRH3 (0.51) | HRH3HRH1MAPTMAPK1KDM2B | |
| SCHEMBL1787581 | 0.79 | HRH3 (0.48) | HRH3HRH1KDM2B | |
| SCHEMBL2264905 | 0.77 | HRH3 (0.49) | HRH3HRH1HTR2CKCNH2MCHR1 | |
| SCHEMBL2194239 | 0.77 | HRH3 (0.51) | HRH3HRH1ADRA1AMAPTMAPK1 | |
| SCHEMBL2188621 | 0.77 | HRH3 (0.51) | HRH3HRH1ADRA1AMAPTMAPK1 | |
| SCHEMBL5661749 | 0.77 | HRH3 (0.53) | HRH3HRH1KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083315-A1 | COMPOUNDS AND THEIR USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011083315-A1 | COMPOUNDS AND THEIR USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-07-14 | — | — | WO | disclosed |