SCHEMBL22708372

SCHEMBL22708372

c1ccc(-c2cccc(-c3nc(-n4c5ccccc5c5c6ccccc6c6c7ccc(-c8ccccc8)cc7sc6c54)nc4c3sc3ccccc34)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 7/20 0.37
LIMK2 P53671 1/20 0.31
PIM1 P11309 1/20 0.30
PIM3 Q86V86 1/20 0.30
PIM2 Q9P1W9 1/20 0.30
PIK3CA P42336 1/20 0.30
PI4KA P42356 1/20 0.30
PI4KB Q9UBF8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22708667 0.96 LIMK1 (0.38) LIMK1LIMK2PIM1PIM3PIM2
SCHEMBL17305618 0.96 LIMK1 (0.31) LIMK1PIM1PIM3PIM2
SCHEMBL22708373 0.94 LIMK1 (0.35) LIMK1
SCHEMBL17297606 0.93 LIMK1 (0.32) LIMK1PIM1PIM3PIM2
SCHEMBL19985984 0.92 LIMK1 (0.30) LIMK1
SCHEMBL17297396 0.91
SCHEMBL17297533 0.91 TNKS (0.33) LIMK1
SCHEMBL22708750 0.91 LIMK1 (0.35) LIMK1PIM1PIM3PIM2PIK3CA
SCHEMBL17305672 0.90 PIM1 (0.32) LIMK1PIM1PIM3PIM2
SCHEMBL17297374 0.90 LIMK1 (0.30) LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588110-B2 Heterocyclic compound and organic light emitting device comprising the same LT MATERIALS CO., LTD. (KR) 2023-02-21 US disclosed
US-20200373499-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LT MATERIALS CO., LTD. (KR) 2020-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11588110-B2 Heterocyclic compound and organic light emitting device comprising the same CRY1, CYP1A1, CYP1B1 LIMK1 541/4885LIMK2 1771/4885PIM1 1126/4885
US-20200373499-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CYP1A1, CYP1B1 LIMK1 541/4885LIMK2 1771/4885PIM1 1126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.