Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22709886 | 0.88 | HTR2C (0.30) | HTR2C | |
| SCHEMBL28501696 | 0.77 | — | — | |
| SCHEMBL28501694 | 0.77 | — | — | |
| SCHEMBL23841610 | 0.76 | — | — | |
| SCHEMBL23074958 | 0.73 | KDM4E (0.40) | — | |
| SCHEMBL29116617 | 0.72 | KRAS (0.31) | — | |
| SCHEMBL28500433 | 0.72 | KRAS (0.31) | — | |
| SCHEMBL19637232 | 0.72 | NUDT1 (0.33) | — | |
| SCHEMBL23074821 | 0.71 | C5AR1 (0.42) | — | |
| SCHEMBL23075033 | 0.71 | C5AR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020236940-A1 | KRAS G12C INHIBITORS AND USES THEREOF | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-11-26 | — | — | WO | disclosed |