Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.81 |
| ▸ | DRD1 | P21728 | 2/20 | 0.81 |
| ▸ | DRD3 | P35462 | 7/20 | 0.59 |
| ▸ | DRD4 | P21917 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | DRD5 | P21918 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362530 | 0.90 | DRD2 (1.00) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL7788774 | 0.90 | DRD2 (1.00) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL7788379 | 0.81 | DRD2 (0.81) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL7781190 | 0.81 | DRD2 (0.81) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL22710197 | 0.81 | DRD2 (0.53) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL8742154 | 0.81 | DRD2 (0.80) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL7781207 | 0.81 | DRD2 (0.80) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL7788407 | 0.80 | DRD2 (0.78) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL7788401 | 0.80 | DRD2 (0.78) | DRD2DRD1DRD3DRD4HTR1A | |
| SCHEMBL7785685 | 0.80 | DRD2 (0.78) | DRD2DRD1DRD3DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234274-A1 | NEW CATECHOLAMINE PRODRUGS FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | H. LUNDBECK A/S (DK) | 2020-11-26 | — | — | WO | disclosed |