Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL17503196 | 0.88 | MAPT (0.45) | ACHEMAPTALDH1A1MEN1LMNA | |
| SCHEMBL10061347 | 0.83 | MAPT (0.49) | ACHEMAPTALDH1A1LMNAPTGS2 | |
| Dimethylamine SCHEMBL17503198 | 0.83 | MGAM (0.50) | ACHEMAPTMEN1LMNAKMT2A | |
| SCHEMBL17503194 | 0.82 | ACHE (0.60) | ACHEMAPTALDH1A1MEN1LMNA | |
| SCHEMBL608070 | 0.79 | ACHE (0.56) | ACHEMAPTALDH1A1MEN1LMNA | |
| SCHEMBL608069 | 0.79 | ACHE (0.56) | ACHEMAPTALDH1A1MEN1LMNA | |
| SCHEMBL610088 | 0.76 | ACHE (0.43) | ACHEALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL610089 | 0.76 | ACHE (0.43) | ACHEALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL610608 | 0.73 | CYP2C9 (0.50) | ACHEMAPTALDH1A1MEN1LMNA | |
| SCHEMBL610609 | 0.73 | CYP2C9 (0.50) | ACHEMAPTALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038621-B1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RES INSTITUTE (US) | 2020-12-02 | — | — | EP | disclosed |