SCHEMBL22712960

SCHEMBL22712960

[N-]=[N+]=NCC(=O)NCCCCC(NC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 19/20 0.61
▸ RIMKLA Q8IXN7 1/20 0.51
▸ NAALAD2 Q9Y3Q0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145414 1.00 FOLH1 (0.61) FOLH1RIMKLANAALAD2
SCHEMBL18145412 1.00 FOLH1 (0.61) FOLH1RIMKLANAALAD2
SCHEMBL14721740 0.90 FOLH1 (0.53) FOLH1
SCHEMBL31095116 0.89 FOLH1 (0.60) FOLH1RIMKLANAALAD2
SCHEMBL22342625 0.89 FOLH1 (0.52) FOLH1RIMKLANAALAD2
SCHEMBL15498130 0.89 FOLH1 (0.52) FOLH1RIMKLANAALAD2
SCHEMBL16802279 0.87 FOLH1 (0.57) FOLH1
SCHEMBL28516521 0.85 FOLH1 (0.58) FOLH1
SCHEMBL16241003 0.85 FOLH1 (0.58) FOLH1
SCHEMBL26848385 0.83 FOLH1 (0.53) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 — — US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 — — US disclosed
US-10894807-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2021-01-19 — — US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885RIMKLA 360/4885NAALAD2 31/4885
US-10894807-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885RIMKLA 360/4885NAALAD2 31/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885RIMKLA 360/4885NAALAD2 31/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885RIMKLA 360/4885NAALAD2 31/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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