Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516521 | 0.98 | FOLH1 (0.58) | FOLH1 | |
| SCHEMBL16241003 | 0.98 | FOLH1 (0.58) | FOLH1 | |
| SCHEMBL31095116 | 0.95 | FOLH1 (0.60) | FOLH1 | |
| SCHEMBL16800300 | 0.94 | FOLH1 (0.50) | FOLH1 | |
| SCHEMBL16641921 | 0.88 | FOLH1 (0.54) | FOLH1 | |
| SCHEMBL16645390 | 0.88 | FOLH1 (0.62) | FOLH1 | |
| SCHEMBL22712960 | 0.87 | FOLH1 (0.61) | FOLH1 | |
| SCHEMBL18145412 | 0.87 | FOLH1 (0.61) | FOLH1 | |
| SCHEMBL18145414 | 0.87 | FOLH1 (0.61) | FOLH1 | |
| SCHEMBL31384213 | 0.87 | NOD1 (0.52) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222617-B1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-3222617-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | The Johns Hopkins University (US) | 2017-09-27 | — | — | EP | disclosed |
| EP-2408755-B1 | Urea-based peptide compounds useful for detecting inter alia prostate cancer | UNIV JOHNS HOPKINS (US) | 2017-05-03 | — | — | EP | disclosed |
| US-9056841-B2 | PSMA-targeting compounds and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-06-16 | — | — | US | disclosed |